Osteophytes and fracture calluses are both examples of new bone formation in the body. Osteophytes are a hallmark radiographic finding of osteoarthritis (OA), while fracture calluses are formed during fracture healing. Our new study explores the similarities and differences of these two structures, adding insight into the factors that may influence osteophyte formation. Check out our work in the Mechanobiology Special Issue of the Journal of Orthopaedic Research.
Osteophytes and fracture calluses share developmental milestones and are diminished by unloading. Hsia AW, Emami AJ, Tarke FD, Cunningham HC, Tjandra PM, Wong A, Christiansen BA, Collette NM. Journal of Orthopaedic Research.