Armaun wins Best Poster Presentation!

The 2017 UC Davis Biomedical Engineering Graduate Group (BMEGG) Student Research Conference was a great success once again! The conference opened with a talk from keynote speaker, Dr. Claudia Fischbach-Teschl of Cornell University, and had two speaker sessions and two poster sessions. Presentations were diverse, ranging from cardiovascular imaging techniques to the neuroscience of learning. Allison and Armaun presented two posters on osteophyte formation during post-traumatic osteoarthritis and systemic bone loss after fracture, respectively. At the end of the conference, the best oral presentation, best poster presentation, and the people’s choice award were presented certificates.

Congratulations to Armaun for winning Best Poster Presentation!

 

IMG_3812
Armaun won Best Poster Presentation for his poster, Systemic Bone Loss Following Femoral Fracture in Mice: A Mechanism for Increased Fracture Risk. 
FullSizeRender (3)
Armaun with Jenna Harvestine (Best Oral Presentation), Rafael Shimkunas (People’s Choice Oral Presentation), and Dr. Kent Leach (BME Chair). 

 

 

 

 

 

Fun at ORS

The Christiansen Lab had a great time at this year’s ORS in San Diego, CA!

2017-03-21 14.39.06
Great talk, Stephanie!
2017-03-20 21.23.31
The lab gets together for dinner at The Knotty Barrel.

 

17310247_395711447463654_3622089486371825873_o
We caught up with other Aggies and some family to beat the “Escape from the Aliens” challenge at Ryptic Room Escape!

 

 

 

Abstracts accepted to ORS!

The Christiansen Lab has 3 posters and 1 podium presentation for ORS 2017 in San Diego, CA!

Podium Presentation

Stephanie Telek: Loss of Bone Stiffness at a Distant Skeletal Site Following Femoral Fracture in Mice

Posters

Armaun Emami: Age-Dependent Systemic Bone Loss and Recovery Following Femoral Fracture in Mice

Allison Hsia: Osteophyte Formation and the Effect of Mechanical Loading: Comparisons to Fracture Healing in Mice

Franklin Tarke: Comparison of Knee Injury Threshold During Tibial Compression Based on Limb Orientation in Mice

 

Congratulations Stephanie, Armaun, Allison, and Franklin!

 

Collette et al. 2016 featured on News-Medical.net

Our work with the Loots Lab at Lawrence Livermore National Labs has been featured on News-Medical.net! The study is titled, “Sostdc1 deficiency accelerates fracture healing by promoting the expansion of periosteal mesenchymal stem cells,” and will be published in Bone in July 2016.

Read the News-Medical.net report here: http://www.news-medical.net/news/20160602/Sostdc1-gene-may-play-vital-role-in-fracture-healing-process.aspx

Osteophyte development restabilizes the knee at the cost of range of motion

Our recent study, Osteophyte Formation After ACL Rupture in Mice is Associated With Joint Restabilization and Loss of Range of Motion, published in the Journal of Orthopaedic Research examined osteophyte development throughout the full time course of osteoarthritis (OA) and its effect on joint function. We used our noninvasive ACL rupture mouse model of post-traumatic OA (PTOA) to investigate how osteophyte formation correlated with changes in joint stability, characterized by anterior-posterior joint laxity, and range of motion (ROM). Stability and ROM both increased immediately after ACL rupture, but began decreasing only 2 weeks post-injury. Stability was restored to control levels after 8 weeks of injury, but ROM in injured limbs was significantly less than that of uninjured knees. These changes in joint function correlated well with osteophyte growth, but only if early chondrophyte development was also taken into consideration. This study suggests that while osteophytes do play a role in joint stabilization during PTOA, chondrophyte formation must be taken into consideration. Few studies currently examine chondrophyte formation, and these findings emphasize the importance of increasing our understanding of chondrophytes in osteophyte formation and OA progression.

Be sure to check out our study in the Journal of Orthopaedic Research!

Hsia et al. J Orthop Res (2016). DOI: 10.1002/jor.23252.